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Retina Arter Tıkanıklıkları ve Tedavisi...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Bilateral Optic Disc Drusen
Vascular Endothelial Growth Factor and Anti VEGF Agents...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Retina Arter Tıkanıklıkları ve Tedavisi...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Morning Glory Syndrome Associated with Retinochoroidal Coloboma...
Santral Retina Ven Dal Tıkanıklıklarında Tedavi...
Journal of Retina-Vitreous 2018 , Vol 27 , Num 4
Turkish Abstract Abstract PDF Similar Articles Mail to Author
Comparing Results of Intravitreal Afl ibercept and Ranibizumab Injections at Patients with Neovascular Age Related Macular Degeneration and Pigment Epithelial Detachment
Meltem Güzin ALTINEL1, Ayşe Yağmur KANRA1, Yelda BUYRU1
1Uz. Dr., İstanbul Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, Istanbul, Türkiye
2Uz. Dr., İstanbul Sultanbeyli Dünya Göz Hastanesi, Göz Hastalıkları Kliniği, Istanbul, Türkiye
3Doç. Dr., İstanbul Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, Istanbul, Türkiye
Purpose: To evaluate the effects of three doses of intravitreal ranibizumab (RAN) and afl ibercept (AFL) on pigment epithelial detachment (PED) in neovascular age related macular degeneration (N-AMD).

Methods: We searched 92 patients’ data with PED and n-AMD. The patients with RAP and PCV, irregular visits, the history of intravitreal injection or PDT were excluded. There were 13 patients at AFL and 11 patients at RAN group. Data on BCVA, CMT, PED types and height, intraretinal and subretinal fluid were evaluated.

Results: The mean CMT and BCVA were not signifi ciantly different between groups before injections (p> 0.05). At both groups the change of CMT was significiantly different after injections (AFL p: 0.025, RAN p: 0.01). The BCVA change was not significiantly different at AFL group (p: 0,063) but it was signifi ciantly different at RAN group (p: 0.007). After injections, PED height change was significiantly different at each group (AFL p: 0.002, RAN p:0.003). The change of fibrovascular PEDs was similar to serous PEDs.

Conclusion: At AFL and RAN groups, after initial 3 doses of injections, the changes of morphological features were similar, RAN was better for BCVA changes. Keywords : Retina, aflibercept, ranibizumab, ped

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