A complete ocular examination, color vision testing, automated static perimetry, optical coherence tomography (OCT) and fundus fl uorescein angiography (FFA) were performed. OCT and FFA fi ndings were revealed a central serous retinopathy in the right eye in a patient who use sertraline for more than a year. In conclussion, the patients who use sertralin should be aware of the potential risk of developing CSR or the other macular changes. Keywords :