2Asis. Dr., Kayseri Eğitim ve Araştırma Hastanesi, Göz Kliniği, Kayseri - TÜRKİYE Purpose: To compare effect of intravitreal dexamethasone implant in eyes with cystoid macular edema secondary to branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO).
Methods: A total of 40 patients treated with Ozurdex injection; 20 patients with CRVO and 20 patients with BRVO were retrospectively reviewed. Complete ophthalmologic examination including measurement of best-corrected visual acuity (BCVA), IOP measurement with goldmann applanation tonometry and fundus examination was performed. After diagnosis central macular thickness (CMT) measurement with Heidelberg Spectralis OCT and fundus fluorescein angiography was also performed. One month after Ozurdex injection BCVA, IOP and OCT measurements were performed.
Results: In the BRVO group the mean BCVA was 0,8 ± 0.2 logMAR and 1,0 ± 0.2 logMAR in the CRVO group at baseline (p=0,133). The mean CMT was 705±252 ?m and 713±268 ?m respectively (p=0,961). One month after the Ozurdex injection, the mean BCVA was 0,4 ± 0.2 logMAR in the BRVO group and 0,6 ± 0.3 logMAR in the CRVO group. BCVA was signifi cantly improved in both groups (p<0.001 and p<0.001 respectively). The mean CMT was 268±132 ?m in the BRVO group and 328±154 ?m in the CRVO group after Ozurdex injection. The mean CMT signifi cantly decreased in both groups (p<0.001 and p<0.001 respectively).
Conclusion: The properties of macular edema secondary to BRVO and CRVO and response to the treatment were similar. Ozurdex injection is effective for the treatment of both diseases.
Keywords : Retinal vein occlusion, macular edema, Ozurdex