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¹Uz. Dr., Gazi Üniversitesi Tıp Fakültesi, Göz Hastalıkları Ana Bilim Dalı, Ankara, Türkiye
²Prof. Dr., Gazi Üniversitesi Tıp Fakültesi, Göz Hastalıkları Ana Bilim Dalı, Ankara, Türkiye Persistent fetal vasculature (PFV), also known as persistent hyperplastic primary vitreous, is a congenital developmental malformation of the eye, caused by the failure of involution of the primary vitreous and hyaloid vasculature. The severity of the disease may vary depending on the affected intraocular structures and anatomical variations, and the broad spectrum of clinical presentations makes PFV challenging for surgical management. The proper selection of surgical techniques is critical to prevent complications and achieve favorable outcomes and highly depends on knowledge of the type, location, and extent of the disease. The aim of this work is to describe the clinical, anatomical features and variations of PFV, as well as to review the principles and pearls for successful surgical management in the current literature and our clinical experience. Keywords : Persistent fetal vasculature; PFV; Persistent hyperplastic primary vitreous; anterior retinal elongation; surgical management