Materials and Methods: This cross-sectional cohort study was conducted on healthy pregnant and non-pregnant women. Macular fl ow area (superfi cial, deep, and choriocapillaris [CC]), superfi cial and deep vessel density, foveal avascular zone (FAZ) area, central foveal thickness (CFT), and subfoveal choroidal thickness (SFCT) were measured using OCTA.

Results: We evaluated 23 eyes of 23 pregnant women with mean age of 31.5±4.1 (26-43) years and 23 eyes of 23 age-matched controls (mean age: 30.5±3.9 [23-43] years). Superfi cial, deep, and CC macular fl ow areas were measured as 16.48±2.1, 14.55±0.8, and 18.71±1.1 in the pregnant women and 13.64±1.1, 13.97±0.6, and 17.63±0.4 in controls, respectively. In addition, superfi cial and deep vessel densities were signifi cantly greater in the pregnant women than controls in all areas (foveal, parafoveal, temporal, superior, nasal, inferior) (P<0.05 for all). There were no signifi cant differences in FAZ area, CFT or SFCT between the groups (P>0.05 for all).

Conclusion: Retinochoroidal micro-vascular fl ow and vessel density in the macular area were increased in pregnant women compared to nonpregnant controls. The clinical relevance of these alterations should be evaluated in further studies. Keywords : Macular micro-circulation, Optical coherence tomography angiography, Pregnancy