Materials and Methods: Thirty-four eyes of 34 patients with unilateral chronic central serous chorioretinopathy (Group 1; involved eyes, Group 2; fellow eyes) and 28 right eyes of 28 age and gender matched subjects (Group 3) were included to study. All participants underwent a detailed ophthalmic examination and an optical coherence tomography obtained by enhanced dept imaging mode (EDI-OCT). Choroidal thickness, total choroidal area, luminal area, stromal area and choroidal vascularity index were calculated with Image J program.

Results: The mean choroidal thickness was 411.47±120.16 (228-674) in Group 1 376.64±73.345 (213-578) in Group 2 and 289.93±47.495 (220-372) in Group 3. Choroidal thickness was significantly higher in Group 1 and 2 than Group 3, but it was statistically similar between Group1 and 2. The mean total choroidal area was 1.66±0.48 (0.58-2.51) in Group 1, 1.60±0.54 (0.63-2.68) in Group 2 and 1.39±0.26 (0.99- 1.94) in Group 3. Total choroidal area, luminal area and choroidal vascularity index were significantly higher in Group 1 and Group 2. Choroidal vascularity indexes were 0.55±0.26 (0.18-0.64), 0.34±0.06 (0.17-0.42), 0.28±0.04 (0.20-0.35) in Group 1, 2 and 3, respectively. It was signifi cantly higher in Group 1 and 2 than Group 3.

Conclusion: Choroidal thickness was increased in patients with central serous chorioretinopathy and their fellow eyes. Also, choroidal vascular structural changes may occur in both eyes of patients. Keywords : Air, diabetic retinopathy, pars plana vitrectomy, perfl uoropropane, silicone oil