Material and Methods: We retrospectively reviewed data of six patients who were diagnoses with posterior scleritis and followed up between 2010 and 2020. In addition to detailed ophthalmological examination, optical coherence tomography (OCT), enhanced depth imaging-OCT, B-scan ultrasonography (US), fundus fluorescein angiography and magnetic resonance imaging, if needed, were obtained.

Results: Of the patients, 4 (66.7%) were female and 2 (33.3%) were male with mean age of 33.3±12.2 (15-49) years. The mean follow-up was 26.8±21.32 (6-58) months. All cases had unilateral involvement at presentation. The most common symptoms were pain exacerbated with eye movements and impaired vision. There was comorbid anterior scleritis in only 2 cases (33.3%). Serous retinal detachment was observed in 5 patients (83.3%) while optic disc edema in 3 patients (50%), scleral thickening and T-sign in all cases. There was comorbid autoimmune disease in 3 patients (%50). High-dose corticosteroids were given in all cases at acute phase of the disease. In 4 patients (66.7%), systemic immunosuppressive therapy was given concurrently. In one patient (16.7%), biological agents were given in addition to combined immunosuppressive therapy. Remission was achieved in all cases.

Conclusion: Posterior scleritis is an uncommon and vision threatening disease which can easily be misdiagnosed. Good visual and clinical outcomes can be achieved with early diagnosis and appropriate treatment. Keywords : Posterior Scleritis, Scleritis, Imaging, Treatment, Prognosis