Turkish Abstract Abstract Article PDF Similar Articles

Gazi Üni. Tıp Fak. Göz Hast. ABD. Ocular toxbplasmosis accounts of 30% to 50% of all posterior uveitis. Generally, reactivation occurs between 10 and 35 years age and average recurrence number is 2,7. Thirtythree eyes of 27 cases of ocular toxoplasmosis were studied retrospectively. Anti-toxoplasma IgG's were positive and IgM's were negative in all cases. Acute inflamatory lesions that threaten the destruction of the macula and optic nerve were present in 12 eyes. Seven out of 12 eyes were treated with pyrimethamine, co-trimoxazole, folinic acid and corticosteroid, where as, 5 of 12 eyes were treated with clindamycine, co-trimoxazole and corticosteroid for 4-6 weeks. After treatment with these drug regimens, visual acuity imporvement were detected in all cases and no difference was found between pyrimethamine group and clindamycine group. Keywords : Ocular toxoplasmosis, diagnosis, treatment