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Ankara Üniversitesi Tıp Fakültesi Göz Hast. A.D. Purpose: To investigate the quantitative assessment of macular edema secondary to central or branch retinal vein occlusion with foveal thickness measurements by optical coherence tomography (OCT).
Material and methods: Thirty eight eyes of 38 cases examined between October 2000-May 2002, with central or branch retinal vein occlusion were included in the study. At initial examination and during follow-up examinations at 3-6 month intervals, complete ophthalmic examination was done, color fundus photographs were taken and fluorescein angiography was performed. Foveal thickness measurements were taken in macular cross-section images obtained with optical coherence tomography. Control group included thirty-nine eyes of 33 healthy objects without eye pathology. Foveal thickness measurements were obtained from macular OCT images and compared with the values of study group.
Results: At initial examination, there was sponge-like retinal swelling in 34 %, cystoid macular edema in 34 %, serous macular edema in 19.2 % and mixed edema in 12.8 % of 38 cases (11 of them had central, 27 of them had branch retinal vein occlusion). In the study group, the mean foveal thickness at initial examination (590.2 ± 45 µm) was significantly higher than the mean value at last visit (403.1± 53 µm). These values were also significantly higher than the mean foveal thickness in control group (177.1 ± 19.4 µm). There was negative correlation between mean foveal thickness measurements and visual acuities at initial and final examinations.
Conclusion: Optical coherence tomography is a useful technique for noninvasive, objective and quantitative assessment of macular edema secondary to retinal vein occlusions with foveal thickness measurements. Keywords : Central retinal vein occlusion, branch retinal vein occlusion, macular edema, optical coherence tomography