Methods: Twenty-nine eyes were included in this retrospective cohort study. All eyes were newly diagnosed as BRVO and were treated with intravitreal injections of aflibercept. After three-months loading doses, patients were treated with a single dose of afl ibercepts if needed. The best-corrected visual acuity (BCVA) and the central macular thickness (CMT) were recorded at each monthly visit.

Results: The mean ages of patients were 61.3±7.6 years. The mean BCVA was 52.2±8.5 letters at baseline, 70.1±11.2 letters at the first year (p<0.001), 69.7±12.5 letters at the second year (p<0.001). The mean CMT was 555±102 µm at baseline; 285±50 µm at the first year (p<0.001), 270±52 µm at the second year (p<0.001). In the first year, the mean number of injections was 5.9±1.2 whereas in the second year it was 2.1±0.9.

Conclusion: These long-term real-life results suggest that the intravitreal afl ibercept is an effective treatment regimen for eyes with macular edema in BRVO. Keywords : Aflibercept, branch retinal vein occlusion, macular edema, long-term results