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¹S. B. Okmeydanı Eğitim ve Araştırma Hastanesi Göz Kliniği, İstanbul, Doç. Dr.
²S. B. Okmeydanı Eğitim ve Araştırma Hastanesi Göz Kliniği, İstanbul, Asist. Dr.
³Acıbadem Göz Kliniği, İstanbul, Doç. Dr.
⁴İstanbul Retina Enstitüsü, İstanbul, Doç. Dr. Purpose: To evaluate the effect of photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSCR) and choroidal neovascularisation (CNV) associated with CSCR.
Materials and Methods: Between July 2003 and May 2005 in the Retina Department of Okmeydanı Education and Desearch Hospital Ophthalmology Clinic, 9 eyes of 9 patients were included in the study. Two of them had chronic CSCR and 7 had CSCR associated with subfoveal or juxtafovel CNV. The diagnosis was confirmed by routine ophthalmological examination, ophthalmoscopy, fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), and optical coherence tomography (OCT). Eight of them were male and 1 was female. One of the patients with CNV also had diabetes mellitus (DM).
Results: Mean age of the patients was 45.9 (±7.7). In 8 of the 9 eyes the leakage stopped in about 3 months with 1 PDT session. In 8 of the 9 eyes 1 session was sufficient and in 7 of them the visual acuity improved 4 lines (8-44 letters in ETDRS). Six eyes had CNV and 1 eye had chronic CSCR (44 letters increase). In the other patient with chronic CSCR, visual acuity remained stable. Two sessions of PDT were performed in the patient with CNV and DM. An 8-line decrease in visual acuity was observed related to scar formation in the macula, in this case. No complication or side effect related to the therapy was observed.
Conclusion: Although we need larger and comparative studies, PDT is an effective and safe procedure in the treatment of chronic CSCR. Early treatment may be important for visual prognosis in chronic cases. Keywords : Chronic CSCR, CNV, PDT