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¹GATA Haydarpaşa Eğit. Hast., Göz Hastalıkları Kliniği, İstanbul, Yard. Doç. Dr.
²GATA Haydarpaşa Eğit. Hast., Göz Hastalıkları Kliniği, İstanbul, Asist. Öğr.
³GATA Haydarpaşa Eğit. Hast., Göz Hastalıkları Kliniği, İstanbul, Prof.Dr. Purpose: The purpose of the current study is to present optic coherence tomography (OCT) and autofluorescence (AF) finding of patients with chronic central serous chorioretinopathy (CSC).
Materials and Methods: Fifteen eyes of 15 patients diagnosed as chronic CSC in our retina department within the last two years was investigated retrospectively. All patients underwent complete ophthalmic examination, fluorescein angiography, AF image (blue and infrared light), OCT imaging. A scanning laser ophthalmoscope (HRA2, Heidelberg Retina Angiograph 2) was used for FA and AF imaging. Nidek brand third generation spectral domain OCT was used for OCT imaging.
Results: OCT imaging revealed subretinal granular aggregation especially in patients with prolonged serous detachment. These aggregates were observed as hyperautofluorescent mottling in AF imaging. Retinal pigment epithelial irregularities observed with OCT sections corresponding to leaking site were seen as hypoautofluorescecnt in AF imaging.
Conclusion: In normal retinal physiology, photoreceptors continuously spread out their discoid outer segments into the subretinal space and they phagocytosed by the RPE. In the case of CSC with neurosensory retinal detachment the cycle disrupts. However photoreceptor outer segments continue to elongate and spreading towards the subretinal fluid and appear subretinal granular deposits. These granules can be visualize by OCT and AF imaging noninvasively. Keywords : Central serous chorioretinopathy, optical coherence tomography, Autofluorescence, lipofuscin, melanin